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The establishment of the BB Unit is to provide the human expertise and resources in biostatistics and bioinformatics to exploit fully the results of our research and the plethora of biological information available within the international bioscience community.

We aim to service the growing cluster of bioscience groups within Wales , share our expertise and develop novel applications for the international bioscience community through collaboration between ourselves and other research groups.

We aim to :

 

  Provide expertise and assistance in complex genetic and biocomputational analysis.

 

  Develop novel bioanalytical and bioinformatics tools to address the ever increasing challenges within the bioscience community.

The areas of our expertise include

Complex phenotypic-genotypic analysis - development and application of sophisticated statistical techniques for identifying the patterns of the complex relationships between disease phenotypes and genetic data via linkage and association analyses. These will allow for multiple genetic and environmental effects and interactions between them.

Microarray analysis - exploiting conventional statistical approaches in addition to neural networks and machine learning technology.

Analysis of mutational data - application of complexity analysis for assigning a possible mechanism of mutagenesis to micro-deletions/insertions, indels, gross deletions and translocations causing various genetic disorders.

Database construction - provision and maintenance of sophisticated databases to provide easy and open access to the numerous phenotypic and genotypic datasets held by bioscience groups across Wales

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The Biostatistics and Bioinformatics Unit - Copyright 2003